The bidirectional nature of microbiome-epithelial cell interactions
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The article explores the complex bidirectional interactions between the gut microbiome and intestinal epithelial cells. Some key points:
The microbiome and intestinal epithelium have developed a network of interactions that maintain intestinal homeostasis. These interactions are bidirectional.
The functions of the intestinal epithelium are compartmentalized into specific subtypes of intestinal epithelial cells.
The microbiome and its metabolic products specifically influence different epithelial cell subtypes.
The article examines the mechanisms by which the microbiome regulates the function of intestinal epithelial cells and, conversely, how different epithelial cell subtypes cooperate in regulating the microbiome.
In summary, the work delves into the bidirectional nature of interactions between the microbiome and intestinal epithelial cells and how these interactions are crucial for maintaining intestinal homeostasis. The article therefore provides an overview of the current state of research in this field.
Source:https://pubmed.ncbi.nlm.nih.gov/32653776/
The microbiome and intestinal epithelium have developed a network of interactions that maintain intestinal homeostasis. These interactions are bidirectional.
The functions of the intestinal epithelium are compartmentalized into specific subtypes of intestinal epithelial cells.
The microbiome and its metabolic products specifically influence different epithelial cell subtypes.
The article examines the mechanisms by which the microbiome regulates the function of intestinal epithelial cells and, conversely, how different epithelial cell subtypes cooperate in regulating the microbiome.
In summary, the work delves into the bidirectional nature of interactions between the microbiome and intestinal epithelial cells and how these interactions are crucial for maintaining intestinal homeostasis. The article therefore provides an overview of the current state of research in this field.
Source:https://pubmed.ncbi.nlm.nih.gov/32653776/